Wield

Press [w] to wield a weapon. To attack a monster in melee, try to move into its square. To use a ranged weapon, such as a bow, wield the weapon, then [T]hrow or [F]ire the ammunition. It is not necessary to wield a thrown weapon, such as a dagger or darts.

Wielding an item, of course, requires touching it, so be sure to wear gloves before wielding something you don't want to touch.